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Spectroscopic and computational investigation of three Cys-to-Ser mutants of nickel superoxide dismutase: insight into the roles played by the Cys2 and Cys6 active-site residues
Nickel-dependent superoxide dismutase (Ni-SOD) is a member of a class of metalloenzymes that protect aerobic organisms from the damaging superoxide radical (O(2)(·−)). A distinctive and fascinating feature of NiSOD is the presence of active-site nickel–thiolate interactions involving the Cys2 and Cy...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997571/ https://ncbi.nlm.nih.gov/pubmed/20333422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-010-0641-2 |
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