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Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers

Organometallic chemistry offers novel concepts in structural diversity and molecular recognition that can be used in drug design. Here, we consider DNA recognition by η(6)-arene Ru(II) anticancer complexes by an induced-fit mechanism. The stereochemistry of the dinuclear complex [((η(6)-biphenyl)RuC...

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Hlavní autoři: Chen, Haimei, Parkinson, John A., Nováková, Olga, Bella, Juraj, Wang, Fuyi, Dawson, Alice, Gould, Robert, Parsons, Simon, Brabec, Viktor, Sadler, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC299748/
https://ncbi.nlm.nih.gov/pubmed/14657383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2434016100
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