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Perturbation analysis: a simple method for filtering SNPs with erroneous genotyping in genome-wide association studies
We introduce a simple and yet scientifically objective criterion for identifying SNPs with genotyping errors due to poor clustering. This yields a metric for assessing the stability of the assigned genotypes by evaluating the extent of discordance between the calls made with the unperturbed and pert...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997476/ https://ncbi.nlm.nih.gov/pubmed/18261185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2007.00422.x |
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