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Perturbation analysis: a simple method for filtering SNPs with erroneous genotyping in genome-wide association studies

We introduce a simple and yet scientifically objective criterion for identifying SNPs with genotyping errors due to poor clustering. This yields a metric for assessing the stability of the assigned genotypes by evaluating the extent of discordance between the calls made with the unperturbed and pert...

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Detalhes bibliográficos
Main Authors: Teo, YY, Small, KS, Clark, TG, Kwiatkowski, DP
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997476/
https://ncbi.nlm.nih.gov/pubmed/18261185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2007.00422.x
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