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Overexpression of TGF-β(1) Gene Induces Cell Surface Localized Glucose-Regulated Protein 78-Associated Latency-Associated Peptide/TGF-β

TGF-β plays a crucial role in immune regulation. It has been reported that pro–TGF-β, latency-associated peptide (LAP), latent TGF-β and/or active TGF-β (LAP/TGF-β) is localized on the cell surface of Foxp3(+) regulatory T cells. However, the molecular mechanism(s) of how LAP/TGF-β is anchored on th...

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Detalhes bibliográficos
Main Authors: Oida, Takatoku, Weiner, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997468/
https://ncbi.nlm.nih.gov/pubmed/20720212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904121
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