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TGF-β Induces Surface LAP Expression on Murine CD4 T Cells Independent of Foxp3 Induction

BACKGROUND: It has been reported that human FOXP3(+) CD4 Tregs express GARP-anchored surface latency-associated peptide (LAP) after activation, based on the use of an anti-human LAP mAb. Murine CD4 Foxp3(+) Tregs have also been reported to express surface LAP, but these studies have been hampered by...

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Detalhes bibliográficos
Main Authors: Oida, Takatoku, Weiner, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991360/
https://ncbi.nlm.nih.gov/pubmed/21124798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015523
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