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Arterial Calcification Is Driven by RAGE in Enpp1–/– Mice

BACKGROUND/AIMS: Ectopic osteochondral differentiation, driven by ENPP1-catalyzed generation of the chondrogenesis and calcification inhibitor inorganic pyrophosphate (PP(i)), promotes generalized arterial calcification of infancy. The multiligand receptor for advanced glycation end-products (RAGE),...

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Detalhes bibliográficos
Main Authors: Cecil, Denise L., Terkeltaub, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997448/
https://ncbi.nlm.nih.gov/pubmed/21099228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000318805
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