Aflatoxin B(1)-Associated DNA Adducts Stall S Phase and Stimulate Rad51 foci in Saccharomyces cerevisiae

AFB(1) is a potent recombinagen in budding yeast. AFB(1) exposure induces RAD51 expression and triggers Rad53 activation in yeast cells that express human CYP1A2. It was unknown, however, when and if Rad51 foci appear. Herein, we show that Rad53 activation correlates with cell-cycle delay in yeast a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Fasullo, Michael, Chen, Yifan, Bortcosh, William, Sun, Minzeng, Egner, Patricia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE-Hindawi Access to Research 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997344/
https://ncbi.nlm.nih.gov/pubmed/21151658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/456487
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky