RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes.
We report on investigations aimed at detecting mutated RAS genes in a variety of preleukemic disorders and leukemias of myeloid origin. DNA transfection analyses (tumorigenicity assay) and hybridization to mutation-specific oligonucleotide probes established NRAS mutations in codon 12 or 61 of 4/9 a...
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| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1987
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299726/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3122217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9228 |
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