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Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies

HIV-1 envelope glycoprotein gp41 undergoes large conformational changes to drive fusion of viral and target cell membranes, thereby exhibiting at least three distinct conformations during the viral entry process. Neutralizing antibodies against gp41 block HIV-1 infection by targeting its membrane pr...

詳細記述

保存先:
書誌詳細
主要な著者: Frey, Gary, Chen, Jia, Rits-Volloch, Sophia, Freeman, Michael M., Zolla-Pazner, Susan, Chen, Bing
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997185/
https://ncbi.nlm.nih.gov/pubmed/21076402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1950
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