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Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies
HIV-1 envelope glycoprotein gp41 undergoes large conformational changes to drive fusion of viral and target cell membranes, thereby exhibiting at least three distinct conformations during the viral entry process. Neutralizing antibodies against gp41 block HIV-1 infection by targeting its membrane pr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997185/ https://ncbi.nlm.nih.gov/pubmed/21076402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1950 |
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