Mature Chief Cells Are Cryptic Progenitors for Metaplasia in the Stomach

BACKGROUND & AIMS: Gastric cancer evolves in the setting of a pathologic mucosal milieu characterized by both loss of acid-secreting parietal cells and mucous cell metaplasias. Indeed, mucous cell metaplasia is considered the critical preneoplastic lesion for gastric cancer. Previous investigati...

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Autori principali: NAM, KI TAEK, LEE, HYUK–JOON, SOUSA, JOSANE F., WEIS, VICTORIA G., O’NEAL, RYAN L., FINKE, PAUL E., ROMERO–GALLO, JUDITH, SHI, GUANGLU, MILLS, JASON C., PEEK, RICHARD M., KONIECZNY, STEPHEN F., GOLDENRING, JAMES R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997152/
https://ncbi.nlm.nih.gov/pubmed/20854822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.09.005
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