CD4(+)CD25(+ )T regulatory cells from FIV(+ )cats induce a unique anergic profile in CD8(+ )lymphocyte targets

BACKGROUND: Using the FIV model, we reported previously that CD4(+)CD25(+ )T regulatory (Treg) cells from FIV(+ )cats are constitutively activated and suppress CD4(+)CD25(- )and CD8(+ )T cell immune responses. In an effort to further explore Treg-mediated suppression, we asked whether Treg cells ind...

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Main Authors: Fogle, Jonathan E, Tompkins, Wayne A, Tompkins, Mary B
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997086/
https://ncbi.nlm.nih.gov/pubmed/21092106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-97
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