Regulation of immunoglobulin transcription rates and mRNA processing in proliferating normal B lymphocytes by activators of protein kinase C.

Immunoglobulin gene expression in normal splenic B lymphocytes stimulated with lipopolysaccharide was selectively down-regulated by anti-IgM antibodies and a protein-kinase C-activating phorbol ester, phorbol 12,13-dibutyrate. This control was concomitant with a decreased rate of transcription of th...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Högbom, E, Mårtensson, I L, Leanderson, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3122213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9135
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