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Regulation of immunoglobulin transcription rates and mRNA processing in proliferating normal B lymphocytes by activators of protein kinase C.

Immunoglobulin gene expression in normal splenic B lymphocytes stimulated with lipopolysaccharide was selectively down-regulated by anti-IgM antibodies and a protein-kinase C-activating phorbol ester, phorbol 12,13-dibutyrate. This control was concomitant with a decreased rate of transcription of th...

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Detalhes bibliográficos
Main Authors: Högbom, E, Mårtensson, I L, Leanderson, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299707/
https://ncbi.nlm.nih.gov/pubmed/3122213
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