Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice

BACKGROUND: Glucagon-like peptide-1 (GLP-1) is recognized as an important regulator of glucose homeostasis. Efforts to utilize GLP-1 mimetics in the treatment of diabetes have yielded clinical benefits. A major hurdle for an effective oral therapy has been the difficulty of finding a non-peptidic GL...

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Autors principals: He, Min, Su, Haoran, Gao, Weiwei, Johansson, Stina M., Liu, Qing, Wu, Xiaoyan, Liao, Jiayu, Young, Andrew A., Bartfai, Tamas, Wang, Ming-Wei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997064/
https://ncbi.nlm.nih.gov/pubmed/21151924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014205
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