Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model

BACKGROUND: Due to the use of organophosphates (OP) as pesticides and the availability of OP-type nerve agents, an effective medical treatment for OP poisonings is still a challenging problem. The acute toxicity of an OP poisoning is mainly due to the inhibition of acetylcholinesterase (AChE) in the...

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Main Authors: Wagner, Sylvia, Kufleitner, Jürgen, Zensi, Anja, Dadparvar, Miriam, Wien, Sascha, Bungert, Judith, Vogel, Tikva, Worek, Franz, Kreuter, Jörg, von Briesen, Hagen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997055/
https://ncbi.nlm.nih.gov/pubmed/21151975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014213
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