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Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693
BACKGROUND: Inappropriate activation of AKT signaling is a relatively common occurrence in human tumors, and can be caused by activation of components of, or by loss or decreased activity of inhibitors of, this signaling pathway. A novel, pan AKT kinase inhibitor, GSK690693, was developed in order t...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996947/ https://ncbi.nlm.nih.gov/pubmed/20604938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-419 |
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