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Presynaptic α(2)δ-3 is required for synaptic morphogenesis independent of its Ca(2+) - channel functions

Synaptogenesis involves the transformation of a growth cone into synaptic boutons specialized for transmitter release. In Drosophila embryos lacking the α(2)δ-3 subunit of presynaptic, voltage-dependent Ca(2+) channels, we find that motor neuron terminals fail to develop synaptic boutons and cytoske...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kurshan, Peri T., Oztan, Asli, Schwarz, Thomas L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996863/
https://ncbi.nlm.nih.gov/pubmed/19820706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2417
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