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An activated c-Ha-ras allele blocks the induction of muscle-specific genes whose expression is contingent on mitogen withdrawal.

During myogenesis, induction of muscle-specific genes is subject to negative control by polypeptide mitogens and type-beta transforming growth factor. Since transduction of growth factor signals may require proteins encoded by cellular ras oncogenes, we have tested whether a mutationally altered Har...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Payne, P A, Olson, E N, Hsiau, P, Roberts, R, Perryman, M B, Schneider, M D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3122209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.8956
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