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Structure and folding of a designed knotted protein

A very small number of natural proteins have folded configurations in which the polypeptide backbone is knotted. Relatively little is known about the folding energy landscapes of such proteins, or how they have evolved. We explore those questions here by designing a unique knotted protein structure....

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Detaylı Bibliyografya
Asıl Yazarlar: King, Neil P., Jacobitz, Alex W., Sawaya, Michael R., Goldschmidt, Lukasz, Yeates, Todd O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996448/
https://ncbi.nlm.nih.gov/pubmed/21068371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007602107
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