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Detoxifying carcinogenic polyhalogenated quinones by hydroxamic acids via an unusual double Lossen rearrangement mechanism

Hydroxamic acids, which are best-known for their metal-chelating properties in biomedical research, have been found to effectively detoxify the carcinogenic polyhalogenated quinoid metabolites of pentachlorophenol and other persistent organic pollutants. However, the chemical mechanism underlying su...

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Bibliografiset tiedot
Päätekijät: Zhu, Ben-Zhan, Zhu, Jun-Ge, Mao, Li, Kalyanaraman, Balaraman, Shan, Guo-Qiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996439/
https://ncbi.nlm.nih.gov/pubmed/21076034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010950107
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