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Multicatalytic, asymmetric Michael/Stetter reaction of salicylaldehydes and activated alkynes
We report the development of a multicatalytic, one-pot, asymmetric Michael/Stetter reaction between salicylaldehydes and electron-deficient alkynes. The cascade proceeds via amine-mediated Michael addition followed by an N-heterocyclic carbene-promoted intramolecular Stetter reaction. A variety of s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996425/ https://ncbi.nlm.nih.gov/pubmed/20639467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002830107 |
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