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Simple strategy for synthesis of optically active allylic alcohols and amines by using enantioselective organocatalysis

A simple organocatalytic one-pot protocol for the construction of optically active allylic alcohols and amines using readily available reactants and catalyst is presented. The described reaction is enabled by an enantioselective enone epoxidation/aziridination-Wharton-reaction sequence affording two...

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Detalhes bibliográficos
Main Authors: Jiang, Hao, Holub, Nicole, Anker Jørgensen, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996415/
https://ncbi.nlm.nih.gov/pubmed/20547884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914523107
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