Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse

BACKGROUND: Several active ingredients proposed as vaginal microbicides have been shown paradoxically to increase susceptibility to infection in mouse genital herpes (HSV-2) vaginal susceptibility models and in clinical trials. In addition, "inactive ingredients" (or excipients) used in to...

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Bibliographic Details
Main Authors: Moench, Thomas R, Mumper, Russell J, Hoen, Timothy E, Sun, Mianmian, Cone, Richard A
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996397/
https://ncbi.nlm.nih.gov/pubmed/21087496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-331
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