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Role of Individual Subunits of the Neurospora crassa CSN Complex in Regulation of Deneddylation and Stability of Cullin Proteins

The Cop9 signalosome (CSN) is an evolutionarily conserved multifunctional complex that controls ubiquitin-dependent protein degradation in eukaryotes. We found seven CSN subunits in Neurospora crassa in a previous study, but only one subunit, CSN-2, was functionally characterized. In this study, we...

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Hlavní autoři: Wang, Jiyong, Hu, Qiwen, Chen, Huijie, Zhou, Zhipeng, Li, Weihua, Wang, Ying, Li, Shaojie, He, Qun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996332/
https://ncbi.nlm.nih.gov/pubmed/21151958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001232
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