The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators

In eukaryotic chromosomes, DNA replication initiates at multiple origins. Large inter-origin gaps arise when several adjacent origins fail to fire. Little is known about how cells cope with this situation. We created a derivative of Saccharomyces cerevisiae chromosome III lacking all efficient origi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Theis, James F., Irene, Carmela, Dershowitz, Ann, Brost, Renee L., Tobin, Michael L., di Sanzo, Fabiana M., Wang, Jian-Ying, Boone, Charles, Newlon, Carol S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996327/
https://ncbi.nlm.nih.gov/pubmed/21151954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001227
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky