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Modeling Conformational Ensembles of Slow Functional Motions in Pin1-WW
Protein-protein interactions are often mediated by flexible loops that experience conformational dynamics on the microsecond to millisecond time scales. NMR relaxation studies can map these dynamics. However, defining the network of inter-converting conformers that underlie the relaxation data remai...
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Главные авторы: | , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Public Library of Science
2010
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996313/ https://ncbi.nlm.nih.gov/pubmed/21152000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001015 |
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