Modeling Conformational Ensembles of Slow Functional Motions in Pin1-WW

Protein-protein interactions are often mediated by flexible loops that experience conformational dynamics on the microsecond to millisecond time scales. NMR relaxation studies can map these dynamics. However, defining the network of inter-converting conformers that underlie the relaxation data remai...

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Bibliographic Details
Main Authors: Morcos, Faruck, Chatterjee, Santanu, McClendon, Christopher L., Brenner, Paul R., López-Rendón, Roberto, Zintsmaster, John, Ercsey-Ravasz, Maria, Sweet, Christopher R., Jacobson, Matthew P., Peng, Jeffrey W., Izaguirre, Jesús A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996313/
https://ncbi.nlm.nih.gov/pubmed/21152000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001015
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