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Modeling Conformational Ensembles of Slow Functional Motions in Pin1-WW
Protein-protein interactions are often mediated by flexible loops that experience conformational dynamics on the microsecond to millisecond time scales. NMR relaxation studies can map these dynamics. However, defining the network of inter-converting conformers that underlie the relaxation data remai...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996313/ https://ncbi.nlm.nih.gov/pubmed/21152000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001015 |
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