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Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.

In primary cultures of cerebellar granule cells, protein kinase C (PKC) translocation and activation can be triggered by the stimulation of excitatory amino acid neurotransmitter receptors. Glutamate evokes a dose-related translocation of 4-beta-[3H]phorbol 12,13-dibutyrate ([3H]-P(BtO)2) binding si...

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Bibliografiska uppgifter
Huvudupphovsmän: Vaccarino, F, Guidotti, A, Costa, E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC299615/
https://ncbi.nlm.nih.gov/pubmed/2825205
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