Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.

Using a sensitive histofluorescence staining method that allows for a quantitation of neuronal death, we compared the protective effects of gangliosides (a group of naturally occurring glycosphingolipids), phencyclidine (PCP), and MK-801 (dibenzocyclohepteneimine) on glutamate- and kainate-induced n...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Favaron, M, Manev, H, Alho, H, Bertolino, M, Ferret, B, Guidotti, A, Costa, E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7351
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