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The Regulation of Factor IXa by Super-sulfated Low Molecular Weight Heparin
Super-sulfated low molecular weight heparin (ssLMWH) inhibits the intrinsic tenase (factor IXa-factor VIIIa) complex in an antithrombin-independent manner. Recombinant factor IXa with alanine substitutions in the protease domain (K126A, N129A, K132A, R165A, R170A, N178A, R233A) were assessed with re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996140/ https://ncbi.nlm.nih.gov/pubmed/20945941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100906q |
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