Efficient osteoclast differentiation requires local complement activation

Previous studies using blocking antibodies suggested that bone marrow (BM)–derived C3 is required for efficient osteoclast (OC) differentiation, and that C3 receptors are involved in this process. However, the detailed underlying mechanism and the possible involvement of other complement receptors r...

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Bibliographic Details
Main Authors: Tu, Zhidan, Bu, Hong, Dennis, James E., Lin, Feng
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996112/
https://ncbi.nlm.nih.gov/pubmed/20709903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-263590
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