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Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis
The stromal signals that promote B lymphopoiesis remain poorly understood. Hedgehog (Hh) signaling promotes B lymphopoiesis in a non–cell-autonomous fashion in vitro, and depletion of the Hh effector Smoothened (Smo) from stromal cells is associated with the loss of osteoblastoid markers. These obse...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774210/ https://ncbi.nlm.nih.gov/pubmed/29167177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-793539 |
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