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Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis

The stromal signals that promote B lymphopoiesis remain poorly understood. Hedgehog (Hh) signaling promotes B lymphopoiesis in a non–cell-autonomous fashion in vitro, and depletion of the Hh effector Smoothened (Smo) from stromal cells is associated with the loss of osteoblastoid markers. These obse...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Lu, Wenyan, Dordai, Dominic, Huso, David, Desiderio, Stephen
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774210/
https://ncbi.nlm.nih.gov/pubmed/29167177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-793539
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