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Identification of a gene that regulates expression of M protein, the major virulence determinant of group A streptococci.

By using Tn916 insertional mutagenesis, we have identified mry (M protein RNA yield), a gene required for high-level expression of the M protein, an essential virulence determinant of the group A streptococcus. The mry::Tn916 mutation causes a reduction by a factor of approximately equal to 50 in th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Caparon, M G, Scott, J R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299609/
https://ncbi.nlm.nih.gov/pubmed/2446327
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