FRS2α Regulates Erk Levels to Control a Self-Renewal Target Hes1 and Proliferation of FGF-Responsive Neural Stem/Progenitor Cells

Fibroblast growth factor (FGF) is among the most common growth factors used in cultures to maintain self-renewal and proliferative capabilities of a variety of stem cells, including neural stem cells (NSCs). However, the molecular mechanisms underlying the control by FGF have remained elusive. Studi...

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Detalhes bibliográficos
Main Authors: Sato, Takuya, Shimazaki, Takuya, Naka, Hayato, Fukami, Shin-Ichi, Satoh, Yasushi, Okano, Hideyuki, Lax, Irit, Schlessinger, Joseph, Gotoh, Noriko
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Tissue-Specific Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996081/
https://ncbi.nlm.nih.gov/pubmed/20652960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.488
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