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Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis

Proteases in the skin are essential to epidermal permeability barrier homeostasis. In addition to their direct proteolytic effects, certain proteases signal to cells by activating protease-activated receptors (PARs), the G-protein-coupled receptors. The expression of functional PAR-2 on human skin a...

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Detalhes bibliográficos
Main Authors: Lee, Sang Eun, Jeong, Se Kyoo, Lee, Seung Hun
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995962/
https://ncbi.nlm.nih.gov/pubmed/20879045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2010.51.6.808
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