Protease-activated receptor-2 mediates the expression of inflammatory cytokines, antimicrobial peptides, and matrix metalloproteinases in keratinocytes in response to Propionibacterium acnes

Propionibacterium acnes (P. acnes) has been known to produce various exogenous proteases, however, their role in acne pathogenesis remains largely unknown. Proteases elicit cellular responses, at least in part, via proteinase-activated receptor-2 (PAR-2), which is known to mediate inflammation and i...

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Bibliografiske detaljer
Main Authors: Lee, Sang Eun, Kim, Ji-Min, Jeong, Se Kyoo, Jeon, Jeong Eun, Yoon, Hyun-Ju, Jeong, Min-Kyung, Lee, Seung Hun
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970807/
https://ncbi.nlm.nih.gov/pubmed/20697725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00403-010-1074-z
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