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An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice

AIMS/HYPOTHESIS: Loss of circadian clocks from all tissues causes defective glucose homeostasis as well as loss of feeding and activity rhythms. Little is known about peripheral tissue clocks, so we tested the hypothesis that an intrinsic circadian clock of the pancreas is important for glucose home...

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Détails bibliographiques
Auteurs principaux: Sadacca, L. A., Lamia, K. A., deLemos, A. S., Blum, B., Weitz, C. J.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995870/
https://ncbi.nlm.nih.gov/pubmed/20890745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1920-8
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