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Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor
Inactivation of von Hippel-Lindau tumor suppressor protein (pVHL) is associated with von Hippel-Lindau disease, an inherited cancer syndrome, as well as the majority of patients with sporadic clear cell renal carcinoma (RCC). While the involvement of pVHL in oxygen sensing through targeting HIFα sub...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995849/ https://ncbi.nlm.nih.gov/pubmed/20802534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.395 |
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