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Emerging Concepts and Approaches for Chemokine-Receptor Drug Discovery

IMPORTANCE OF THE FIELD: Chemokine receptors are G protein-coupled receptors (GPCRs) most noted for their role in cell migration. However, inappropriate utilization or regulation of these receptors is implicated in many inflammatory diseases, cancer and HIV, making them important drug targets. AREAS...

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Detalhes bibliográficos
Main Authors: O’Hayre, Morgan, Salanga, Catherina L., Handel, Tracy M., Hamel, Damon J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995586/
https://ncbi.nlm.nih.gov/pubmed/21132095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2010.525633
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