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Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

Recent studies using magnetic resonance spectroscopy have shown that decreased insulin-stimulated muscle glycogen synthesis due to a defect in insulin-stimulated glucose transport activity is a major factor in the pathogenesis of type 2 diabetes. The molecular mechanism underlying defective insulin-...

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Autori principali: Morino, Katsutaro, Petersen, Kitt Falk, Shulman, Gerald I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995546/
https://ncbi.nlm.nih.gov/pubmed/17130651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db06-S002
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