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Structural determinants of PINK1 topology and dual subcellular distribution
BACKGROUND: PINK1 is a mitochondria-targeted kinase that constitutively localizes to both the mitochondria and the cytosol. The mechanism of how PINK1 achieves cytosolic localization following mitochondrial processing remains unknown. Understanding PINK1 subcellular localization will give us insight...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995477/ https://ncbi.nlm.nih.gov/pubmed/21092208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-90 |
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