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A threshold sample-enrichment approach in a clinical trial with heterogeneous subpopulations
BACKGROUND: Large comparative clinical trials usual target a wide-range of patients population in which subgroups exist according to certain patients’ characteristics. Often, scientific knowledge or existing empirical data support the assumption that patients’ improvement is larger among certain sub...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995455/ https://ncbi.nlm.nih.gov/pubmed/20685769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510378695 |
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