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Adjusting for Misclassification in a Stratified Biomarker Clinical Trial (†)
Clinical trials utilizing predictive biomarkers have become a research focus in personalized medicine. We investigate the effects of biomarker misclassification on the design and analysis of stratified biomarker clinical trials. For a variety of inference problems including marker-treatment interact...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107031/ https://ncbi.nlm.nih.gov/pubmed/24733510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6164 |
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