No mitochondrial DNA deletions but more D-loop point mutations in repeated pregnancy loss

PURPOSE: Repeated pregnancy loss (RPL) occurs in 1 out of 300 couples, and the cause of about 50% of them remains idiopathic. Mitochondria have an important role in human development through ATP production and their involvement in apoptosis. METHODS: 96 RPL and 96 control females were used to invest...

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Bibliographic Details
Main Authors: Seyedhassani, Seyed Mohammad, Houshmand, Massoud, Kalantar, Seyed Mehdi, Modabber, Glayol, Aflatoonian, Abbas
Format: Artigo
Language:Inglês
Published: Springer US 2010
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995430/
https://ncbi.nlm.nih.gov/pubmed/20499271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-010-9435-2
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