Translocation of the Na(+)/H(+) exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signalling

The Na(+)/H(+) exchanger NHE1 is a highly regulated membrane protein that is required for pH homoeostasis in cardiomyocytes. The activation of NHE1 leads to proton extrusion, which is essential for counteracting cellular acidity that occurs following increased metabolic activity or ischaemia. The ac...

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Bibliographic Details
Main Authors: Lawrence, Scott P., Holman, Geoffrey D., Koumanov, Françoise
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995423/
https://ncbi.nlm.nih.gov/pubmed/20868366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100717
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