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Translocation of the Na(+)/H(+) exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signalling

The Na(+)/H(+) exchanger NHE1 is a highly regulated membrane protein that is required for pH homoeostasis in cardiomyocytes. The activation of NHE1 leads to proton extrusion, which is essential for counteracting cellular acidity that occurs following increased metabolic activity or ischaemia. The ac...

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Detalhes bibliográficos
Main Authors: Lawrence, Scott P., Holman, Geoffrey D., Koumanov, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995423/
https://ncbi.nlm.nih.gov/pubmed/20868366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100717
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