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Short RNA duplexes guide sequence-dependent cleavage by human Dicer

Dicer is a member of the double-stranded (ds) RNA-specific ribonuclease III (RNase III) family that is required for RNA processing and degradation. Like most members of the RNase III family, Dicer possesses a dsRNA binding domain and cleaves long RNA duplexes in vitro. In this study, Dicer substrate...

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Bibliografiske detaljer
Main Authors: Bergeron, Lucien Junior, Perreault, Jean-Pierre, Elela, Sherif Abou
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995407/
https://ncbi.nlm.nih.gov/pubmed/20974746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2346510
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