CYP4A2-Induced Hypertension is 20-HETE and Angiotensin II-Dependent

We have previously shown that increased vascular endothelial expression of CYP4A2 leads to 20-HETE-dependent hypertension. The renin-angiotensin system (RAS) is a key regulator of blood pressure. In this study, we examined possible interactions between 20-HETE and RAS. In normotensive (110±3 mmHg) S...

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Autores principales: Sodhi, Komal, Wu, Cheng-Chia, Cheng, Jennifer, Gotlinger, Katherine, Inoue, Kazuyoshi, Goli, Mohan, Falck, John R., Abraham, Nader G., Schwartzman, Michal L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995375/
https://ncbi.nlm.nih.gov/pubmed/20837888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.154559
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